Geistlich Bio-Oss Collagen®

Shop Now

Can collagen expertise reshape your bone substitute procedures?


Creating the leading bone substitute for oral regeneration is where we started—then our Geistlich collagen expertise introduced a whole new treatment dimension.

We encourage you to review the resources available to enhance your understanding of Geistlich Bio-Oss Collagen®, and to shape your regenerative success with a product that is, Exactly Like No Other.

About Geistlich Bio-Oss Collagen®

Geistlich Bio-Oss Collagen® with its 10% collagen formulation, was developed to mimic the role collagen plays in promoting rapid vascularization and epithelial regeneration.1

  • Collagen is a complex tissue that is important in cell growth, repair and regeneration.
  • Early vascularity is encouraged by stimulating angiogenesis and providing the collagen “tracks” along which vascular channels form making it possible for tissue integration and bone formation.
  • It is these very attributes that led to the development of Geistlich Bio-Oss Collagen®, by combining Geistlich Bio-Oss® the most trusted and proven bone substitute granules with the power of collagen to create a product with clear clinical advantages.
  • Studies have shown the use of Geistlich Bio-Oss Collagen® in extraction sockets compensates for buccal bone loss and preserves hard and soft-tissue volume with optimal esthetics (implant site development).

Handling &
Ease of Use

The ability to adapt Geistlich Bio-Oss Collagen® to the specific defect allows for exceptional handling and ease of use.

  • The addition of 10% collagen to Geistlich Bio-Oss® granules results in a product that is pliable and moldable allowing the ability to adapt the material to the morphology of the defect.
  • The material can be easily cut to size and optimally placed for contour augmentation procedures ensuring adequate buccal bone volume.

Unique Properties

This innovation was intentionally designed to stabilize the existing clot in a range of treatments, leading to faster bone regeneration and improved bone quality.2

  • Collagen provides wound adhesion and hemostasis by initiating the clotting cascade.
  • Collagen has the ability to stabilize the existing clot, promote neovascularization and epithelial regeneration.
  • These properties provide the clinical advantages of faster healing and improved bone quality.
  • Studies have shown less buccal dehiscences, increased horizontal bone volume and improved soft-tissue healing when combining Geistlich Bio-Oss Collagen® + Geistlich Bio-Gide® vs DFDBA + a cross-linked membrane.3
Geistlich Bio-Oss Collagen®
Dr. Ueli Grunder
Zurich, Switzerland

Contour Augmentation With Geistlich Bio-Oss Collagen® A 25 Year Follow-Up

Clinical Challenge

The upper premolar had to be removed due to advanced periodontal disease and severe bone loss around the infected tooth. The bone defect was an intra-alveolar defect without dehiscence or fenestration.

Aim / Approach

An early implant placement approach with a healing time of six weeks before implant placement was chosen. The bone augmentation with Geistlich Bio-Oss Collagen® was conducted simultaneously with implant placement. As this patient was treated in 1991, the case is one of the very first clinical applications of Geistlich Bio-Oss Collagen®.

Pre-operative radiograph showing the severe bone defect around the tooth.
Six weeks after tooth extraction, uneventful soft-tissue healing in the post-operative phase is visible.
After flap preparation, an implant was placed in a site with a severe bone defect.
In order to fill up the defect and provide volume stability Geistlich Bio-Oss Collagen® was applied.
After augmentation with Geistlich Bio-Oss Collagen®, the site was covered with a collagen fleece.
Final crown restoration after 6 months post-operative.
The radiograph after 25 years shows a stable bone situation.
The clinical picture after 25 years follow-up presents a very nice and stable bone and soft-tissue situation.


A premolar grafted with Geistlich Bio-Oss Collagen® during implant placement showed good long-term result after 25 years. Satisfactory hard and soft-tissue contour are present 25 years after implantation.


Bone Augmentation L-Shape Technique With Early Implant Placement
Prof. Dr. Ronald Jung
Play VideoDownload PDF
Immediate Mandibular Molar Transition
Dr. Peter Hunt
Play Video Download PDF
Ridge Augmentation and Delayed Implant Placement on an Upper Lateral Incisor
Dr. Daniele Cardaropoli
Play VideoDownload PDF

Surgical Videos

Ridge Preservation after Tooth Extraction (Intact Socket)
PD PhD Ronald Jung
Play Video
Ridge Preservation after Tooth Extraction (Non Intact Socket)
Dr. Arndt Happe
Play Video
Minor Bone Augmentation
Dr. Arndt Happe
Play Video
Shield for Success
Fill the gap on immediate implant placement with Geistlich Bio-Oss Collagen® and Geistlich Bio-Gide® Shape
Play Video

Customer Testimonals

"Geistlich Bio-Oss Collagen® 50mg was the ideal size graft material for placement between the implant and facial plate for maintaining the hard and soft-tissue volume throughout the course of osseointegration and healing."

Dr. Justin Kang

"Geistlich Bio-Oss Collagen® is easy to handle and allows bone grafting procedures to be predictable. The material can be easily trimmed, and manipulated to any defect. It’s collagen make up allows for blood clot stability with better adhesion to the treatment site. While I have used many bone grafting materials in the past 30 years, Geistlich Bio-Oss Collagen® continuously yields successful results. This product can be easily introduced and implemented into your daily practice."

Dr. Mario Vilardi

"I routinely rely on Geistlich Bio-Oss Collagen® in my practice — it's very easy to shape and apply. It is an excellent material for space making defects. It has good hemostatic properties and stays where you place it."

Dr. Alan Meltzer, Voorhees, New Jersey

"Geistlich Bio-Oss Collagen® is an excellent product. It has changed my implant practice."

Dr. Collin M. Stutz, Creve Coeur, MO, USA

"Geistlich Bio-Oss Collagen® is by far, the best and most predictable graft material I have ever used."

Dr. John Heldridge, Edmonds, WA, USA

"Geistlich Bio-Oss Collagen® is the only graft material I use around immediate implants and helps me achieve incredible predictability and success."

Dr. Israel Puterman, Chevy Chase, MD, USA

"When hydrated and placed appropriately, Geistlich Bio-Oss Collagen® makes the procedure more efficient and predictable."

Dr. Leonard E. Schiffman, Woodmere, NY, USA

"Geistlich Bio-Oss Collagen® is the ONLY graft material I use for extraction sockets."

Dr. John Parnoff, New Haven, CT, USA


Publications Database

Geistlich Bio-Oss Collagen® 50mg Indication Sheet

Download PDF
Publications Database

Clinical Perspectives Brochure

Download PDF
Bone Portfolio Brochure

Bone Portfolio Brochure

Download PDF
Product Information

Product Information Brochure

Download PDF
SCPP Infographic

Clinical Study Brochure

Download PDF
Information Flyer

Geistlich Bio-Oss Collagen®
Information Flyer

Download PDF
Publications Database

View More Studies Online

Publications Database

We know you have questions.

At Geistlich Biomaterials, answers are our Specialty.

When you’re talking regeneration, there is no substitute for definitive information from the most knowledgeable people in the field. Call us today to learn more about what makes Geistlich Bio-Oss Collagen® exactly the right treatment solution for your patients.


More than 1000 publications


More than 30 years of clinical experience


More than 165 years of Geistlich collagen competence

Customer Care

Learn more about our full portfolio of products

Bio-Oss Collagen®

Available Sizes:
50mg, 100mg, 250mg, 500mg

Shop Now